COMPOSITION :

Esobest 40 IV Injection: Each vial contains Esomeprazole 40 mg as Esomeprazole

Sodium INN Sterile lyophilized powder and each ampoule contains 5 ml of 0.9%

Sodium Chloride BP for IV injection.

PHARMACOLOGY:

The proton pump inhibitor Esomeprazole inhibits gastric acid by blocking the

hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump)

of the gastric parietal cell. Proton pump inhibitors are effective for short-term

treatment of gastric and duodenal ulcers. Esomeprazole is also used in the

prevention and treatment of NSAID associated gastric ulcers.

INDICATIONS:

Esomeprazole is indicated to relieve from chronic heartburn symptoms and other

symptoms associated with GERD, healing of erosive esophagitis, maintenance of

healing of erosive esophagitis, NSAID associated gastric ulcers, Zollinger-Ellison

Syndrome, Acid related Dyspepsia, Gastric & Duodenal ulcer.