COMPOSITION:
Resol Paediatric Drops: Each ml drops contains Ambroxol Hydrochloride
BP 6 mg.
Resol Syrup: Each 5 ml syrup contains Ambroxol Hydrochloride BP 15 mg.
PHARMACOLOGY:
Ambroxol is a metabolite of Bromhexine. It possesses mucokinetic
(improvement in mucus transport) and secretolytic (liquefies secretions)
properties. Ambroxol stimulates the serous cells of the glands of the
mucous membrane of bronchi, increasing the content of mucus secretion.
The mucolytic effect is associated with depolymerization and splitting of
mucoproteins and mucopolysaccharide fibres, which leads to reduction in
the viscosity of mucus. Expectoration of mucus is facilitated and breathing
is eased considerably. Ambroxol stimulates production of phospholipids of
surfactant by alveolar cells. Ambroxol has anti-inflammatory properties. In
patients with COPD, it improves airway potency. Beside these, Ambroxol
also exhibits anti-oxidant activity. Long-term use is possible because of the
good tolerability of the preparation.