COMPOSITION:
Pregalex 50: Each capsule contains Pregabalin INN 50 mg.
Pregalex 75: Each capsule contains Pregabalin INN 75 mg.
Pregalex 150: Each capsule contains Pregabalin INN 150 mg.
DESCRIPTION:
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-amino-butyric acid (GABA). It does not bind directly to GABA A , GABA B , or benzodiazepine receptors. It binds with high affinity to the alpha 2-delta site (an auxiliary subunit of voltage gated calcium channel) in central nervous system tissues. Oral bioavailability of Pregabalin is 90%. Pregabalin is eliminated largely by renal excretion, and has an elimination half life of about 6.3 hours. Pregabalin can be taken with or without food.