COMPOSITION
Coxsafe 60 Tablet: Each film coated tablet contains Etoricoxib INN 60 mg.
Coxsafe 90 Tablet: Each film coated tablet contains Etoricoxib INN 90 mg.
Coxsafe 120 Tablet: Each film coated tablet contains Etoricoxib INN 120 mg.
PHARMACOLOGY
Etoricoxib is a Nonsteroidal Anti-inflammatory Drug (NSAID) that exhibits anti-
inflammatory, analgesic and antipyretic activities. It is a potent, orally active,
highly selective cyclooxygenase-2 (COX-2) inhibitor within and above the
clinical dose range. COX-2 has been shown to be primarily responsible for the
synthesis of prostanoid mediators of pain, inflammation and fever. Selective
inhibition of COX-2 by Etoricoxib decreases these clinical signs and symptoms
with decreased GI toxicity and without effects on platelets function.
INDICATIONS :
Etoricoxib is indicated for relief of pain and inflammation in Osteoarthritis,
Rheumatoid Arthritis, Ankylosing Spondylitis, Acute Gout, Primary
Dysmenorrhoea, Postoperative Dental Pain & other Chronic Musculoskeletal
Disorders
No review yet