Composition: Nixar Tablet: Each film coated tablet contains Nitazoxanide INN 500 mg. Nixar Suspension: After reconstitution each 5 ml suspension contains Nitazoxanide INN 100 mg.
Pharmacology:
Nitazoxanide, a synthetic antiprozoal agent. Nitazoxanide is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreducatse (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.
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