BIOXIM CAPSULE

Generic Name: Cefixime Trihydrate USP

Therapeutic Name: Antibacterial Drugs

  • Prescription:
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Composition :

Bioxim Capsule: Each capsule contains Cefixime Trihydrate USP equivalent to Cefixime 200 mg.

Bioxim 400 Capsule: Each capsule contains Cefixime Trihydrate USP equivalent to Cefixime 400 mg.

 

Bioxim DS Powder for Suspension: After reconstitution each 5 ml suspension contains Cefixime Trihydrate USP equivalent to Cefixime 200 mg.

Pharmacology :

Cefixime is a broad spectrum cephalosporin antibiotic of third generation for oral administration. It is a bactericidal antibiotic and is stable to hydrolysis by many beta-lactamases.Cefixime kills bacteria by interfering in the synthesis of the bacterial cell wall. Cefixime is highly active against Neisseria gonorrhoeae, Haemophilus influenzae, Moraxella catarrhalis including betalactamase producers, most of the Enterobacteriaceae, betahaemolytic Streptococci (group A & B) and Streptococcus pneumoniae. Cefixime is more active than other oral cephalosporins against Escherichia coli, Klebsiella spp., Proteus mirabilis, Serratia marcescens and Streptococcus pyogenes. 40-50% of an oral dose is absorbed from gastro-intestinal tract, whether taken with meals or not.The plasma half-life is usually about 3 to 4 hours and may be prolonged when there is renal impairment. About 65% is bound to plasma protein.Cefixime is mainly excreted unchanged in bile and urine. Indications : Bioxim is indicated for the treatment of urinary tract infections, upper and lower respiratory tract infections, acute otitis media, gonococcal urethritis and enteric fever.